I use a ProNose as I don't like to use a string holding my nose on either unless the red nose I am using is really big and I know that no amount of spirit gum will keep it on. However, in answer to your question I use:
"Ben Nye's Prosthetic Adhesive"
Basically I put some on my (real) nose and let it dry as well as some on the inside of my (clown) nose and let it dry as well. wait about 5 minutes and apply the nose to my face. It has lasted me 5+ hours, doesn't itch or anything and removal is very easy.
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